For two millennia, medicinal mushrooms have been mainstream in Asia. Now, America is taking notice and interest is rapidly "mushrooming." With the sprouting of this new industry follows issues of ethical quality claims between competing brands.
All medicinal mushroom species are plagued by this. Most fiercely debated is red reishi (Ganoderma lucidum), the most popular of all medicinal mushrooms. So this article will primarily focus on that species, but it's generally applicable to all species of medicinal mushrooms.
The first and perhaps obvious caution is to stay away from cheap mass-produced brands of medicinal mushrooms that may only contain dried and pulverized mushrooms, in which case the medicinal compounds are still inaccessible behind the mushrooms' cell walls.
There are many real therapeutic brands on the market, though. But even among them, there are significant differences. They all claim to be the best, naturally, because they all want to sell their particular brand. So let's sift the data, get the facts straight, and clear up misleading information that is out there.
Below are three common methods for extracting medicinal compounds from reishi. Each method results in different compounds. All groups have been shown to have therapeutic effects in scientific studies.
1. Water Extraction, Hot (polysaccharides and more)
2. Alcohol Extraction (triterpenoids, sterols)
3. Fermentation (arabinoxylanes, etc.)
The water soluble compounds, primarily polysaccharides, are powerful anti-tumor agents, immune enhancers and strong antioxidants. [1]
The alcohol soluble compounds are mainly triterpenoids, a large group of related compounds. Scientific studies suggest they help stabilize cholesterol, blood pressure and clotting. Most importantly, they are the anti-inflammatory compounds so critical to many of reishi's suggested uses, including arthritis, allergies and asthma. [1]
Less researched are the "secondary metabolites" that come from fermenting reishi. "Secondary" because they result when the original medicinal compounds get broken down by bacteria. These new compounds have been shown to possess therapeutic properties that are unique, including immune enhancement, anti-tumor and blood-sugar regulation. [2]
This article is not meant to recommend any particular brand so none will be mentioned by name. But the author does know of two reishi companies (Japanese and American) that both claim only hot water extract of reishi is effective and that alcohol extracts are of no use.
They do that, of course, because they wish to sell their products. However, there is no scientific validity to those claims. All three extraction methods listed above yield important medicinal compounds.
To find the best red reishi products, look for those brands that use at least the first two extraction methods in combination: Hot Water Extraction and Alcohol Extraction. Better yet would be brands that incorporate all three extraction methods, including Fermentation.
Last but not least, remember to look at the form the reishi comes in. If the reishi is able to dissolve completely in water-based drinks like coffee, it's a safe bet that it only contains the water-soluble polysaccharides. An excellent choice as far as coffee goes but an incomplete reishi supplement because it does not include the anti-inflammatory triterpenoid compounds.
Alcohol tinctures, on the other hand, are well worth considering because they may be a blend of water and alcohol extracts. The way to tell is if the tincture is cloudy. When water-soluble polysaccharides get mixed with alcohol, they fall out of solution. Cloudiness in an alcohol tincture indicates high polysaccharide content. Just shake before taking. Tablets and capsules can contain hot water extract, alcohol extract or both. You need to find out from the manufacturer.
[1] Boh B, Berovic M, Zhang J, Zhi-Bin L, 2007. "Ganoderma lucidum and its pharmaceutically active compounds." Biotechnology Annu Rev 13:265-301.
[2] Tang YJ, Zhang W, Zhong JJ, 2009. "Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum." Bioresource Technol. Mar;100(5):1852-9. - 14130
All medicinal mushroom species are plagued by this. Most fiercely debated is red reishi (Ganoderma lucidum), the most popular of all medicinal mushrooms. So this article will primarily focus on that species, but it's generally applicable to all species of medicinal mushrooms.
The first and perhaps obvious caution is to stay away from cheap mass-produced brands of medicinal mushrooms that may only contain dried and pulverized mushrooms, in which case the medicinal compounds are still inaccessible behind the mushrooms' cell walls.
There are many real therapeutic brands on the market, though. But even among them, there are significant differences. They all claim to be the best, naturally, because they all want to sell their particular brand. So let's sift the data, get the facts straight, and clear up misleading information that is out there.
Below are three common methods for extracting medicinal compounds from reishi. Each method results in different compounds. All groups have been shown to have therapeutic effects in scientific studies.
1. Water Extraction, Hot (polysaccharides and more)
2. Alcohol Extraction (triterpenoids, sterols)
3. Fermentation (arabinoxylanes, etc.)
The water soluble compounds, primarily polysaccharides, are powerful anti-tumor agents, immune enhancers and strong antioxidants. [1]
The alcohol soluble compounds are mainly triterpenoids, a large group of related compounds. Scientific studies suggest they help stabilize cholesterol, blood pressure and clotting. Most importantly, they are the anti-inflammatory compounds so critical to many of reishi's suggested uses, including arthritis, allergies and asthma. [1]
Less researched are the "secondary metabolites" that come from fermenting reishi. "Secondary" because they result when the original medicinal compounds get broken down by bacteria. These new compounds have been shown to possess therapeutic properties that are unique, including immune enhancement, anti-tumor and blood-sugar regulation. [2]
This article is not meant to recommend any particular brand so none will be mentioned by name. But the author does know of two reishi companies (Japanese and American) that both claim only hot water extract of reishi is effective and that alcohol extracts are of no use.
They do that, of course, because they wish to sell their products. However, there is no scientific validity to those claims. All three extraction methods listed above yield important medicinal compounds.
To find the best red reishi products, look for those brands that use at least the first two extraction methods in combination: Hot Water Extraction and Alcohol Extraction. Better yet would be brands that incorporate all three extraction methods, including Fermentation.
Last but not least, remember to look at the form the reishi comes in. If the reishi is able to dissolve completely in water-based drinks like coffee, it's a safe bet that it only contains the water-soluble polysaccharides. An excellent choice as far as coffee goes but an incomplete reishi supplement because it does not include the anti-inflammatory triterpenoid compounds.
Alcohol tinctures, on the other hand, are well worth considering because they may be a blend of water and alcohol extracts. The way to tell is if the tincture is cloudy. When water-soluble polysaccharides get mixed with alcohol, they fall out of solution. Cloudiness in an alcohol tincture indicates high polysaccharide content. Just shake before taking. Tablets and capsules can contain hot water extract, alcohol extract or both. You need to find out from the manufacturer.
[1] Boh B, Berovic M, Zhang J, Zhi-Bin L, 2007. "Ganoderma lucidum and its pharmaceutically active compounds." Biotechnology Annu Rev 13:265-301.
[2] Tang YJ, Zhang W, Zhong JJ, 2009. "Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum." Bioresource Technol. Mar;100(5):1852-9. - 14130
About the Author:
Dr. Rafael has worked in the health field since the early 90's, recently focusing on medicinal mushrooms. He partners with Cordyceps Reishi Extracts, LLC on premium reishi extract and cordyceps extract plus the increasingly popular mesima and more.
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